Publications

Table of Contents:

• 2023
• 2022
• 2017 - 2021
• 2012 - 2016
• 2010 - 2011 (Postdoc)
• 2006 - 2009 (Ph.D.)

Representative Publications

2023

• Xing, S.¹, Zhu, Y.¹, You, Y., Wang, S., Wang, H., Ning, M., Jin, H., Liu, Z., Zhang, X., Yu, C. * & Lu, Z. J.* (2023). Cell-free RNA for the liquid biopsy of gastrointestinal cancer. WIREs RNA 14(5):e1791 (¹contributed equally, *co-corresponding authors)

  View Detail | PDF

• Chun Ning¹, Peng Cai¹, Xiaofan Liu¹, Guangtao Li¹, Pengfei Bao, Lu Yan, Meng Ning, Kaichen Tang, Yi Luo, Hua Guo, Lu Chen*, Zhi John Lu *, Jianhua Yin* (2023) A Comprehensive Evaluation of Full-spectrum Cell-free RNAs highlights cell-free RNA fragments for Early-Stage Hepatocellular Carcinoma Detection eBioMedicine 93:104645 (¹contributed equally, *co-corresponding authors)

  View Detail

• Hongke Wang¹, Qing Zhan¹, Hongjie Guo¹, Jiuliang Zhao, Shaozhen Xing, Shanwen Chen, Shuai Zuo, Mengtao Li*, Pengyuan Wang*, Zhi John Lu* (2023) Depletion-assisted multiplexing cell-free RNA sequencing reveals distinct human and microbial signatures in plasma versus extracellular vesicle bioRxiv 10.1101/2023.01.31.526408 (¹contributed equally, *co-corresponding authors)

  Preprint

• Yuhuan Tao¹, Shaozhen Xing¹, Shuai Zuo¹, Pengfei Bao, Yunfan Jin, Yu Li, Yingchao Wu, Shanwen Chen, Xiaojuan Wang, Yumin Zhu, Ying Feng, Xiaohua Zhang, Xianbo Wang, Qiaoran Xi, Qian Lu*, Pengyuan Wang*, Zhi John Lu* (2023) Cell-free multi-omics analysis reveals tumor status-informative signatures in gastrointestinal cancer ptients’ plasma bioRxiv 10.1101/2023.01.31.526431 (¹contributed equally, *co-corresponding authors)

  Preprint

• Xiaofan Liu, Yuhuan Tao, Zilin Cai, Pengfei Bao, Hongli Ma, Kexing Li, Yunping Zhu*, Zhi John Lu* (2023) Pathformer: biological pathway informed Transformer model integrating multi-modal data of cancer bioRxiv 10.1101/2023.05.23.541554 (*co-corresponding authors)

  Preprint

—————————————————66————————————————————

2022

• Shanwen Chen¹, Yunfan Jin¹, Siqi Wang¹, Shaozhen Xing¹, Yingchao Wu, Yuhuan Tao, Yongchen Ma, Shuai Zuo, Xiaofan Liu, Yichen Hu, Hongyan Chen, Yuandeng Luo, Feng Xia, Chuanming Xie, Jianhua Yin, Xin Wang, Zhihua Liu, Ning Zhang, Zhenjiang Zech Xu*, Zhi John Lu*, Pengyuan Wang* (2022) Cancer Type Classification Using Plasma Cell Free RNAs Derived from Human and Microbes. eLife 11:e75181 (¹contributed equally, *co-corresponding authors)

  View Detail

• Haipeng Fu, Tingyu Wang, Xiaohui Kong, Kun Yan, Yang Yang, Jingyi Cao, Yafei Yuan, Nan Wang, Kehkooi Kee, Zhi John Lu & Qiaoran Xi (2022) A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells. Nature Communications 13(1):3984

  View Detail

• Liuqing Yang, Kequan Lin, Lin Zhu, Huili Wang, Shuaishuai Teng, Lijun Huang, Shiyi Zhou, Guanbin Zhang, Zhi John Lu & Dong Wang (2022) Long non-coding RNA DARS-AS1 promotes tumor progression by directly suppressing PACT-mediated cellular stress. Communications Biology 5, 822

  View Detail

• Weihao Zhao¹, Shang Zhang¹, Yumin Zhu, Xiaochen Xi, Pengfei Bao, Ziyuan Ma, Thomas H Kapral, Shuyuan Chen, Bojan Zagrovic, Yucheng T Yang*, Zhi John Lu* (2022) POSTAR3: an updated platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins. Nucleic Acids Research 50(D1):D287-D294 (¹contributed equally, *co-corresponding authors)

  View Detail | Website

• Thomas H Kapral, Fiona Farnhammer, Weihao Zhao, Zhi J Lu and Bojan Zagrovic (2022) Widespread autogenous mRNA–protein interactions detected by CLIP-seq. Nucleic Acids Research, 50(17):9984-9999

  View Detail

—————————————————61————————————————————

2017 - 2021

2021

• Yumin Zhu¹, Siqi Wang¹, Xiaochen Xi¹, Minfeng Zhang¹, Xiaofan Liu, Weina Tang, Peng Cai, Shaozhen Xing, Pengfei Bao, Yunfan Jin, Weihao Zhao, Yinghui Chen, Huanan Zhao, Xiaodong Jia, Shanshan Lu, Yinying Lu, Lei Chen*, Jianhua Yin*, Zhi John Lu* (2021) Integrative analysis of long extracellular RNAs reveals a detection panel of noncoding RNAs for liver cancer. Theranostics 11(1):181-193 (¹contributed equally, *co-corresponding authors)

  View Detail

• Jing Gong¹, Kui Xu¹, Ziyuan Ma, Zhi John Lu & Qiangfeng Cliff Zhang (2021) A deep learning method for recovering missing signals in transcriptome-wide RNA structure profiles from probing experiments. Nature Machine Intelligence 3:995–1006

  View Detail

• Jia Li, Lei Sun, Xue-Liang Peng, Xiao-Ming Yu, Shao-Jun Qi, Zhi John Lu, Jing-Dong J Han, Qin Shen (2021) Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons. PLoS Genetics 17(3):e1009355 View Detail

• Shanwen Chen, Tao Liu, Dingfang Bu, Jing Zhu, Xin Wang, Yisheng Pan, Yucun Liu, Zhi John Lu, Pengyuan Wang (2021）Methylome profiling identifies TCHH methylation in CfDNA as a noninvasive marker of liver metastasis in colorectal cancer. FASEB J. 35(7):e21720

  View Detail

2020

• Shuaishuai Teng¹, Yang Eric Li¹, Ming Yang, Rui Qi, Yiming Huang, Qianyu Wang, Yanmei Zhang, Shanwen Chen, Shasha Li, Kequan Lin, Yang Cao, Qunsheng Ji, Qingyang Gu, Yujing Cheng, Zai Chang, Wei Guo, Pengyuan Wang, Ivan Garcia-Bassets, Zhi John Lu* and Dong Wang* (2020) Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer. Cell Research 30(1):34-49 (¹contributed equally, *co-corresponding authors)

  View Detail

• Yu-Xiang Chen¹, Zhi-yu Xu¹, Xueliang Ge, Suparna Sanyal, Zhi John Lu* and Babak Javid* (2020) Selective translation by alternative bacterial ribosomes. PNAS 117(32):19487-19496 (¹contributed equally, *co-corresponding authors)

  View Detail

• Yu Ma¹, Shang Zhang¹, Chao Bi¹, Chao Mei, Shang-Chuan Jiang, Xiao-Fang Wang, Zhi John Lu* and Da-Peng Zhang* (2020) Arabidopsis exoribonuclease USB1 interacts with the PPR-domain protein SOAR1 to negatively regulate abscisic acid signaling. Journal of Experimental Botany 71(19): 5837-5851 (¹contributed equally, *co-corresponding authors)

  View Detail

• Kequan Lin¹, Lu Li¹, Yifei Dai, Huili Wang, Shuaishuai Teng, Xilinqiqige Bao, Zhi John Lu* and Dong Wang* (2020) A comprehensive evaluation of connectivity methods for L1000 data Briefings in Bioinformatics 21 (6), 2194-2205 (¹contributed equally, *co-corresponding authors)

  View Detail

—————————————————53————————————————————

2019

• Rui Xiao^1,*, Jia-Yu Chen¹, Zhengyu Liang¹, Daji Luo, Geng Chen, Zhi John Lu, Yang Chen, Bing Zhou, Hairi Li, Xian Du, Yang Yang, Mingkui San, Xintao Wei, Wen Liu, Eric Lecuyer, Brenton R. Graveley, Gene W. Yeo, Christopher B. Burge, Michael Q. Zhang, Yu Zhou and Xiang-Dong Fu* (2019) Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription Cell 178, 107–121 (¹contributed equally, *co-corresponding authors)

  View Detail

• Maoguo Luo, Jianbo Bai, Bofeng Liu, Peiqiang Yan, Feifei Zuo, Hongyao Sun, Ye Sun, Xuanhao Xu, Zhihong Song, Yang Yang, Joan Massagué, Xun Lan, Zhi Lu, Ye-Guang Chen, Haiteng Deng, Wei Xie, Qiaoran Xi (2019) H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling Stem Cell Reports 13(4):642-656

  View Detail

• Chang Tan¹, Jingyi Cao¹, Lu Chen¹, Xiaochen Xi, Siqi Wang, Yumin Zhu, Liuqing Yang, Longteng Ma, Dong Wang, Jianhua Yin*, Ti Zhang* and Zhi John Lu* (2019) Noncoding RNAs serve as diagnosis and prognosis biomarkers for hepatocellular carcinoma Clinical Chemistry 65(7):905-915 (¹contributed equally, *co-corresponding authors)

  View Detail

• Yumin Zhu¹, Gang Xu¹, Yucheng T Yang¹, Zhiyu Xu, Xinduo Chen, Binbin Shi, Daoxin Xie, Zhi John Lu*, Pengyuan Wang* (2019) POSTAR2: deciphering the post-transcriptional regulatory logics Nucleic Acids Research (D1):D203-D211 (¹contributed equally, *co-corresponding authors)

  View Detail

• Shasha Li¹, Shuaishuai Teng¹, Junquan Xu, Guannan Su, Yu Zhang, Jianqing Zhao, Suwei Zhang, Haiyan Wang, Wenyan Qin, Zhi John Lu, Yong Guo, Qianyong Zhu and Dong Wang (2019) Microarray is an efficient tool for circRNA profiling. Briefings in Bioinformatics 20(4):1420-1433 (¹contributed equally)

  View Detail

2018

• Zhiyu Xu¹, Long Hu¹, Binbin Shi, SiSi Geng, Longchen Xu, Dong Wang* and Zhi John Lu* (2018) Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events. Nucleic Acids Research 46 (18), e109-e109 (¹contributed equally, *co-corresponding authors)

  View Detail GitHub

• [spotlight]: Binbin Shi and Zhi John Lu* (2018) Decoding Plant RNA Structurome. Molecular Plant 11:3

  View Detail

• J Yuan¹, J Li¹, Y Yang, C Tan, Y Zhu, L Hu, Y Qi*, ZJ Lu* (2018) Stress‐responsive regulation of long non‐coding RNA polyadenylation in Oryza sativa. The Plant Journal 93:5, 814-827 (¹contributed equally, *co-corresponding authors)

  View Detail

• J Gong, D Shao, K Xu, Z Lu, ZJ Lu, YT Yang, QC Zhang (2018) RISE: a database of RNA interactome from sequencing experiments. Nucleic Acids Research 46 (D1), D194-D201

  View Detail

—————————————————44————————————————————

2017

• Yang Eric Li¹, Mu Xiao¹, Binbin Shi¹, Yu-Cheng T. Yang, Dong Wang, Fei Wang, Marco Marcia and Zhi John Lu* (2017) Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA-protein binding sites. Genome Biology 18:169 (¹contributed equally)

  View Detail ePDF Web Site GitHub

• Yang Yang¹, Lei Chen¹, Jin Gu¹, Hanshuo Zhang¹, Jiapei Yuan, Qiuyu Lian, Guishuai Lv, Siqi Wang, Yang Wu, Yu-Cheng T. Yang, Dongfang Wang, Yang Liu, Jing Tang, Guijuan Luo, Yang Li, Long Hu, Xinbao Sun, Dong Wang, Mingzhou Guo, Qiaoran Xi, Jianzhong Xi, Hongyang Wang*, Michael Q. Zhang* and Zhi John Lu* (2017) Recurrently deregulated lncRNAs in hepatocellular carcinoma. Nature Communications 8, 14421 (¹contributed equally, *co-corresponding authors)

  View Details ePDF

• Xiaochen Xi¹, Tianxiao Li¹, Yiming Huang, Jiahui Sun, Yumin Zhu, Yang Yang* and Zhi John Lu* (2017) RNA Biomarkers: Frontier of Precision Medicine for Cancer. Non-Coding RNA3, 9 (¹contributed equally, *co-corresponding authors)

  View Details

• Yang Yang¹, Yu-Cheng T. Yang¹, Jiapei Yuan, Zhi John Lu* and Jingyi Jessica Li* (2017) Large-scale mapping of mammalian transcriptomes identifies conserved genes associated with different cell differentiation states. Nucleic Acids Research 45 (4): 1657-1672 (¹contributed equally, *co-corresponding authors)

  View Details

• Zhonglin Tang^1,*, Yang Wu¹, Yalan Yang, Yu-Cheng T. Yang, Zishuai Wang, Jiapei Yuan, Yang Yang, Chaoju Hua, Xinhao Fan, Guanglin Niu, Yubo Zhang, Zhi John Lu* and Kui Li* (2017) Comprehensive analysis of long non-coding RNAs highlights their spatio-temporal expression patterns and evolutional conservation in Sus scrofa. Scientific Reports 7:43166 (¹contributed equally, * co-corresponding authors)

  View Details ePDF

• Dan Gao, Yingjie Han, Yang Yang, James G Herman, Enqiang Linghu, Qimin Zhan, François Fuks, Zhi John Lu, Mingzhou Guo (2017) Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development. Epigenetics12(7):575-583

  View Details

• Long Hu, Zhiyu Xu, Boqin Hu and Zhi John Lu* (2017) *COME: a robust coding potential calculation tool for lncRNA identification and characterization based on multiple features. ** *Nucleic Acids Research 45 (1): e2

  View Details Web Site GitHub

• Boqin Hu¹, Yu-Cheng T. Yang¹, Yiming Huang, Yumin Zhu and Zhi John Lu* (2017) POSTAR: a platform of post-transcriptional regulation coordinated by RNA binding proteins. Nucleic Acids Research 45 (D1): D104-D114 (¹contributed equally)

  View Details Web Site

—————————————————36————————————————————

2012 - 2016

2016

• Mengrong Liu¹, Yu-Cheng T. Yang¹, Gang Xu, Chang Tan, and Zhi John Lu* (2016) CCG: an integrative resource of cancer protein-coding and long noncoding RNA genes. Discovery Medicine 22 (123): 351-359 (¹contributed equally)

  View Details

• Yang Wu¹, Rihao Qu¹, Yiming Huang¹, Binbin Shi, Mengrong Liu, Yang Li and Zhi John Lu* (2016) RNAex: an RNA secondary structure prediction server enhanced by high-throughput structure probing data. Nucleic Acids Research 44 (W1): W294-W301 (¹contributed equally)

  View Details Web Site

• Jiapei Yuan¹, Ye Zhang¹, Jinsong Dong, Xinbao Sun, Yuzhe Sun, Boon L. Lim, Dong Liu* and Zhi John Lu* (2016) Systematic characterization of novel lncRNAs responding to phosphate starvation in Arabidopsis thaliana. BMC Genomics 17:655 (¹contributed equally, *: co-corresponding authors)

  View Details

• Baoping Cao¹, Nanxi Song¹, Meiying Zhang, Runsheng Chen, Youyong Lu, Runshen Chen*, Zhi John Lu* and Mingzhou Guo* (2016) Systematic study of novel lncRNAs in different gastrointestinal cancer cell lines. Discovery Medicine 21(115):159-171 (¹contributed equally, *: co-corresponding authors)

  View Details

• [review]: Xihao Hu¹, Yang Wu¹, Zhi John Lu and Kevin Y. Yip. (2016) Analysis of Sequencing Data for Probing RNA Secondary Structures and Protein-RNA Binding in Studying Post-Transcriptional Regulations. Briefings in Bioinformatics 17(6): 1032-1043 (¹contributed equally)

  View Details

• Kejia Wen¹, Lijuan Yang¹, Tuanlin Xiong, Chao Di, Danhui Ma, Menghua Wu, Zhaoyu Xue, Xuedi Zhang, Li Long, Weimin Zhang, Jiaying Zhang, Xiaolin Bi, Junbiao Dai, Qiangfeng Zhang, Zhi John Lu and Guanjun Gao (2016) Critical roles of long noncoding RNAs in Drosophila spermatogenesis. Genome Research 26: 1233-1244 (¹contributed equally)

  View Details

• Sibo Tao¹, Ye Zhang¹, Xiaoyue Wang, Xiaofeng Fang, Le Xu, Zhi John Lu and Dong Liu (2016) The THO/TREX complex active in mRNA export suppresses root-associated acid phosphatase activity induced by phosphate starvation. Plant Physiology 171(4):2841-53 (¹contributed equally)

  View Details

• Sai Luo, J. Yuyang Lu, Lichao Liu, Yafei Yin, Chunyan Chen, Xue Han, Bohou Wu, Ronggang Xu, Wei Liu, Pixi Yan, Wen Shao, Zhi Lu, Haitao Li, Jie Na, Fuchou Tang, Jianlong Wang, Yong E. Zhang, Xiaohua Shen (2016) Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells. Cell Stem Cell 21(115):159-171

  View Details

2015

• Yang Wu¹, Binbin Shi¹, Xinqiang Ding, Tong Liu, Xihao Hu, Kevin Y. Yip, Zheng Rong Yang, David H. Mathews and Zhi John Lu* (2015) Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data. Nucleic Acids Research 43(15): 7247-59 (¹contributed equally)

  View Details GitHub

• Long Hu, Chao Di, Mingxuan Kai, Yu-Cheng T. Yang, Yang Li, Yunjiang Qiu, Xihao Hu, Kevin Y. Yip, Michael Q. Zhang and Zhi John Lu* (2015) A common set of distinct features that characterize noncoding RNAs across multiple species. Nucleic Acids Research 43(1): 104-114

  View Details Web Site

• Yu-Cheng T. Yang¹, Chao Di¹, Boqin Hu¹, Meifeng Zhou, Yifang Liu, Nanxi Song, Yang Li, Jumpei Umetsu and Zhi John Lu* (2015) CLIPdb: a CLIP-seq database for protein-RNA interactions. BMC Genomics 16:51 (¹contributed equally)

  View Details Web Site

• Yinghan Fu, Zhengjiang Zech Xu, Zhi J. Lu, Shan Zhao, and David H. Mathews(2015) Discovery of Novel ncRNA Squences in Multiple Genome Alignments on the Basis of Conserved and Stable Secondary Structures. PloS one10(6):e0130200

  View Details

—————————————————24————————————————————

2014

• Chao Di¹, Jiapei Yuan¹, Yue Wu, Jingrui Li, Huixin Lin, Long Hu, Ting Zhang, Yijun Qi, Mark B. Gerstein, Yan Guo and Zhi John Lu* (2014) Characterization of Stress-responsive lncRNAs in Arabidopsis thaliana by Integrating Expression, Epigenetic and Structural Features. The Plant Journal 80(5), 848-861 (¹contributed equally)

  View Details

• Mark B. Gerstein, Joel Rozowsky, Koon-Kiu Yan, Daifeng Wang, Chao Cheng, James B. Brown, Carrie A. Davis, LaDeana Hillier, Cristina Sisu, Jingyi Jessica Li, Baikang Pei, Arif O. Harmanci, Michael O. Duff, Sarah Djebali, Roger P. Alexander,… Chao Di, … Zhi Lu, … Thomas R. Gingeras and Robert Waterston.(2014) Comparative analysis of the transcriptome across distant species. Nature 512:445-448

  View Details

• YC Yang, J Umetsu, ZJ Lu* (2014) Global signatures of protein binding on structured RNAs in Saccharomyces cerevisiae. Science China Life Sciences 57 (1), 22-35 (Tsinghua Special Issue)

  View Details

• Hu X, Wong TKF, Lu ZJ, Chan TF, Lau TCK, Yiu SM and Yip KY. (2014) Computational Identification of Protein Binding Sites on RNAs using High-Throughput RNA Structure-Probing Data. Bioinformatics 30(8), 1049-1055.

  View Details

• B Ren, H Shen, ZJ Lu, H Liu, Y Xu. (2014) The phzA2-G2 Transcript Exhibits Direct RsmA-Mediated Activation in Pseudomonas aeruginosa M18. PloS one 9 (2), e89653

  View Details

2013

• Freeberg MA, Han T,Moresco JJ, Kong A, Yang YC, Lu ZJ, Yates JR, Kim JK. (2013) Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae. Genome Biology 14, R13.

  View Details

• Kudron M, Niu W, Lu Z, Wang G, Gerstein M, Snyder M, Reinke V. (2013) Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs. Genome Biology 14:R5

  View Details

2012

• Tan X, Hu L², Luquette JL, Gao G, Liu YF2, Qu HJ, Xi RB, Lu ZJ², Park PJ & Elledge SJ. (2012) Systematic Identification of Synergistic Drug Pairs Targeting HIV. Nature Biotech 30:1125-1130. (² Lu Lab, School of Life Sciences, Tsinghua University)

  View Details

• Tan X, Lu ZJ², Gao G, Xu QK, Hu L², Fellmann C, Li MZ, Qu HJ, Lowe SW, Hannon GJ & Elledge SJ. (2012) Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy. Proc. Natl. Acad. Sci. U. S. A., 109(3):869-74. (²Lu Lab, School of Life Sciences, Tsinghua University)

  View Details

• The ENCODE Project Consortium# (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74 (# ZJL was a member of ENCODE Consortium)

  View Details

• He C, Li YX, Zhang G, Gu Z, Yang R, Li J, Lu ZJ, Zhou ZH, Zhang C, Wang J. (2012) MiRmat: Mature microRNA Sequence Prediction. PloS one 7 (12), e51673.

  View Details

—————————————————13————————————————————

2010 - 2011 (Postdoc)

• Lu ZJ¹, Yip KY¹, Wang G, Shou C, Hillier LW, et al. (2011) Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data. Genome Research 21: 276-285. (¹contributed equally) [modENCODE special issue]

  View Details

• Niu W, Lu ZJ, Zhong M, Sarov M, Murray JI, et al. (2011) Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome Research 21: 245-254.

  View Details

• The ENCODE Project Consortium (2011) A User’s Guide to the Encyclopedia of DNA Elements (ENCODE). PLoS Biology 9(4):e1001046 (Zhi J. Lu is a member of ENCODE)

  View Details

• Mu XJ, Lu ZJ, Kong Y, Lam HYK, Gerstein MB. (2011) Analysis of genomic variation in non-coding elements using population-scale sequencing data from the 1000 Genomes Project. Nucleic Acids Research 39 (16):7058-7076.

  View Details

• Li Y, Du X, Lu ZJ, Wu D, Zhao Y, et al. (2011) Regulatory Feedback Loop of Two phz Gene Clusters through 5’ Untranslated Regions in Pseudomonas sp. M18.PLoS ONE 6(4): e19413

  View Details

• Cheng C, Yan KK, Hwang W, Qian J, Bhardwaj N, Joel R, Lu ZJ, Niu W, Alves P, Kato M, Gerstein MB. (2011) Construction and analysis of an integrated regulatory network derived from high-throughput sequencing data. PLoS Comput Biol 7: e1002190

  View Details

• Gerstein MB^1,*, Lu ZJ¹, Van Nostrand EL¹, Cheng C¹, Arshinoff BI¹, et al. (2010) Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project Science 330 (6012): 1775-1787 (¹20 co-first authors, *15 co-corresponding authors, ~150 authors in total) [Cover Story]

  View Details

• Zhong M, Niu W, Lu ZJ, Sarov M, Murray JI, et al. (2010) Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response. PLoS Genetics 6(2): e1000848.

  View Details

—————————————————5————————————————————

2006 - 2009 (Ph.D.)

• Lu ZJ, Gloor JW, Mathews DH. (2009) Improved RNA secondary structure prediction by maximizing expedted pair accuracy. RNA 15:1805-1813.

  View Details

• Lu ZJ, Mathews DH. (2008) Efficient siRNA selection using hybridization thermodynamics.Nucleic Acids Research 36:640-647.

  View Details

• Lu ZJ, Mathews DH. (2008) OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics. Nucleic Acids Research 36:W104-W108.

  View Details

• Lu ZJ, Mathews DH. (2008) Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design. Nucleic Acids Research 36:3738-3745.

  View Details

• Lu ZJ, Turner DH, Mathews DH. (2006) A set of nearest neighbor parameters for predicting the enthalpy change of RNA secondary structure formation. Nucleic Acids Research34:4912-4924.

  View Details

More on Google Scholar